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Additional file 3 of Body mass index-associated molecular characteristics involved in tumor immune and metabolic pathways

Figshare2020-09-25 更新2026-04-28 收录

免疫代谢

BMI相关基因

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https://figshare.com/articles/dataset/Additional_file_3_of_Body_mass_index-associated_molecular_characteristics_involved_in_tumor_immune_and_metabolic_pathways/13010777 数据链接链接失效反馈

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Additional file 3. The BMI-related genes.

应用场景：

创建时间：

2020-09-25

免疫代谢

巨噬细胞生态位

Gene expression comparison across CD11b+ cells from Csf2-sufficient and deficient mice. Overall design: Steady state isolated CD11b+ cells from colon lamina propria or solitary isolated lymphoid tissu

NIAID Data Ecosystem70

Disturbed mitochondrial dynamics in CD8+ TIL reinforce epigenetic programming linked with T cell exhaustion

免疫代谢

T细胞耗竭

The metabolic challenges present in tumors attenuate the metabolic fitness and anti-tumor activity of tumor-infiltrating T lymphocytes (TILs). However, it remains unclear whether persistent metabolic

NIAID Data Ecosystem60

D- 2-hydroxyglutarate is an immunometabolite that accumulates in macrophages after TLR activation and inhibits inflammatory responses

免疫代谢

巨噬细胞炎症抑制

Macrophages undergo extensive metabolic rewiring upon activation and this serves many roles beyond the production of energy and anabolic building blocks. So-called immunometabolites that accumulate up

NIAID Data Ecosystem30

Additional file 8: of Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10

转录组学分析

免疫代谢

GSEA core enrichment - Oxphos - IL-10 immunodepleted vs low LPS plasma. (XLS 61 kb)

NIAID Data Ecosystem70

Pro-survival Lipid Sphingosine-1-Phosphate Metabolically Reprograms T cell to Limit its Anti-Tumor Activity

免疫代谢

T细胞功能调控

Sphingosine 1-phosphate (S1P), a pro-tumor survival bioactive lysophospholipid, generated by sphingosine kinase 1 (SphK1), regulates lymphocyte egress into circulation via transducing S1P receptor 1 (

NIAID Data Ecosystem50

Additional file 3 of Body mass index-associated molecular characteristics involved in tumor immune and metabolic pathways

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