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Microarray analysis of in-vitro differentiated murine Th17 cells in the presence of the smac mimetic AT406, or DMSO as control, and undifferentiated naive CD4 T cells.

ChEBI2019-08-15 更新2026-07-12 收录

Th17细胞

免疫调控药物筛选

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-7894 数据链接链接失效反馈

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Microarray analysis of in-vitro differentiated murine Th17 cells in the presence of the smac mimetic AT406, or DMSO as control, and undifferentiated naive CD4 T cells.

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创建时间：

2019-08-15

Th17细胞

自身免疫性疾病免疫病理学

CD4+ T cells that selectively produce interleukin (IL)-17, are critical for host defense and autoimmunity. Crucial for T helper17 (Th17) cells in vivo, IL-23 has been thought to be incapable of drivin

NIAID Data Ecosystem60

Single-cell transcriptional profiling of Th17 cells, differentiated in vitro for 48h [IL1B_IL6_IL23-48h-IL-17A/GFP+]

Th17细胞

自身免疫性脑脊髓炎

Extensive cellular heterogeneity exists within specific immune-cell subtypes classified as a single lineage, but its molecular underpinnings are rarely characterized at a genomic scale. Here, we use s

NIAID Data Ecosystem40

The Swi/Snf chromatin remodeling complex promotes Th17 differentiation by coordinating RORγt-driven epigenetic program. The Swi/Snf chromatin remodeling complex promotes Th17 differentiation by coordinating RORγt-driven epigenetic program

Th17细胞

染色质重塑调控

TH17 cells play a critical role in mucosal immunity and also in multiple autoimmune diseases. The differentiation of TH17 cells is dictated by a master transcription factor, RORγt; however, the mechan

NIAID Data Ecosystem20

Gene expression analysis of WT Th17 versus STAT4 deficient Th17 cells from EAE mice. Gene expression analysis of WT Th17 versus STAT4 deficient Th17 cells from EAE mice

Th17细胞

EAE疾病基因调控

The purpose of this study is to compare transcriptional profiles of WT and STAT4-deficient Th17 cultured cells from mice with experimental autoimmune encephalomyelitis (EAE) using RNA sequencing. WT a

NIAID Data Ecosystem50

Table2_Bazedoxifene Regulates Th17 Immune Response to Ameliorate Experimental Autoimmune myocarditis via Inhibition of STAT3 Activation.DOCX

自身免疫性心肌炎

Th17细胞

Myocarditis is a type of inflammatory cardiomyopathy that has no specific treatment. Accumulating evidence suggests that Th17 cells play a prominent role in the pathogenesis of myocarditis. Interleuki

NIAID Data Ecosystem30

Microarray analysis of in-vitro differentiated murine Th17 cells in the presence of the smac mimetic AT406, or DMSO as control, and undifferentiated naive CD4 T cells.

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