Functional and structural dysfunction of the blood brain barrier (BBB) leads to severe alterations in brain physiology and is believed to trigger neurodegeneration. To investigate the molecular mechan

NIAID Data Ecosystem50

BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq]

血脑屏障转录组学

神经元模型

NIAID Data Ecosystem40

RNA sequencing of blood-brain barrier cells exposed to interleukin-6

炎症机制

血脑屏障转录组学

To study the impact of inflammation on the blood-brarrier permeability we choose to expose hCMEC/D3 cells, a blood-brain barrier cell line, to interleukin-6 as an inflammatory marker. Examination of t

NIAID Data Ecosystem50

RNA-sequencing of brain microvascular endothelial cell dysfunction in an isogenic juvenile iPSC model of Huntington's disease

亨廷顿病模型

血脑屏障转录组学

Huntington's disease (HD) is associated with dysfunction of the blood-brain barrier, including brain microvasscular endothelial cells (BMECs). We report changes in gene expression of induced pluripote

NIAID Data Ecosystem40

BBBomics - Human Blood Brain Barrier Transcriptomics Hub [miRNA-seq]

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