Conditions and resulting inequalities used to constrain the simple subcircuit and define its allowable parameter space (APS).

Condition type and Condition (first 2 columns) describe the rationale behind each condition. The resulting inequality on population steady-state voltages and are given in the 3rd column. These inequalities must hold for typical non-painful fAβ values, which we take to be fAβ ∈ [10, 20] Hz. Vx,max and Vx,min are the maximum and minimum limits on average voltage, respectively, Vx,rest is the resting membrane voltage and Vx,thr is the voltage threshold for firing (x = E, I).