The effect of CDK6 expression on DNA methylation and DNMT3B regulation
收藏NIAID Data Ecosystem2026-05-01 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP248610
下载链接
链接失效反馈官方服务:
资源简介:
We performed methylation analyses in BCR-ABL+ cells either expressing or lacking CDK6 using the next-generation sequencing approach RRBS and identified DNA methylation changes towards both hyper- and hypomethylation. CDK6 mediated methylation changes are largely reverted by CDK6 re-expression in this experimental system. Overall design: 3 BCR-ABL+/CDK6wt cell lines, 3 BCR-ABL+/CDK6-/- cell lines, 3 BCR-ABL+/CDK6-/-+Cdk6 cell lines.
创建时间:
2023-09-26



