Crystal structure of HCV NS5B polymerase with COMPOUND 2
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of HCV NS5B polymerase with COMPOUND 2 Descriptor: 3-{[4-oxo-1-(2,4,6-trifluorobenzyl)-1,4-dihydroquinazolin-6-yl]oxy}-2-(trifluoromethyl)benzamide, GLYCEROL, Genome polyprotein, ... Authors: Coulombe, R. Deposit date: 2013-03-24 Release date: 2013-07-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Molecular Dynamics Simulations and Structure-Based Rational Design Lead to Allosteric HCV NS5B Polymerase Thumb Pocket 2 Inhibitor with Picomolar Cellular Replicon Potency. J.Med.Chem., 57, 2014
创建时间:
2013-03-24



