Patent SAR for MMV390048

Figshare2016-01-11 更新2026-04-08 收录

抗疟疾药物研发

结构-活性关系分析

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https://figshare.com/articles/dataset/Patent_SAR_for_MMV390048/657979/3 数据链接链接失效反馈

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资源简介：

An SAR data set extracted, via SureChemPro, from patent WO211086531, that includes the antimalarial drug candidate MMV390048

创建时间：

2013-03-22

Structure–Activity Relationship Studies of a Novel Class of Transmission Blocking Antimalarials Targeting Male Gametes

抗疟疾药物研发

传播阻断剂优化

Malaria is still a leading cause of mortality among children in the developing world, and despite the immense progress made in reducing the global burden, further efforts are needed if eradication is

NIAID Data Ecosystem70

Enantiopure Benzofuran-2-carboxamides of 1‑Aryltetrahydro-β-carbolines Are Potent Antimalarials In Vitro

抗疟疾药物研发

先导化合物

The tetrahydro-β-carboline scaffold has proven fertile ground for the discovery of antimalarial agents (e.g., MMV008138 (1) and cipargamin (2)). Similarity searching of a publicly disclosed collection

NIAID Data Ecosystem30

An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS

抗疟疾药物研发

先导化合物

In 2010, GlaxoSmithKline published the structures of 13533 chemical starting points for antimalarial lead identification. By using an agglomerative structural clustering technique followed by computat

Figshare2016-02-22 更新20

Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1 H )‑Quinolones with Potent Antimalarial Activity: Structure–Activity and Structure–Property Relationship Studies

抗疟疾药物研发

药物化学优化

Malaria deaths have been decreasing over the last 10–15 years, with global mortality rates having fallen by 47% since 2000. While the World Health Organization (WHO) recommends the use of artemisinin-

NIAID Data Ecosystem40

MOESM2 of The past, present and future of anti-malarial medicines

抗疟疾药物研发

药代动力学

Additional file 2. Biological data for compounds. Tabulation of biological potencies and pharmacokinetic properties for each compound described in Future section of this review.

NIAID Data Ecosystem30

Patent SAR for MMV390048

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