First Total Synthesis of (±)-3-Hydroxy-11-norcytisine: Structure Confirmation and Biological Characterization
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https://figshare.com/articles/dataset/First_Total_Synthesis_of_3_Hydroxy_11_norcytisine_Structure_Confirmation_and_Biological_Characterization/2895157
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资源简介:
The first total synthesis of the natural product 3-hydroxy-11-norcytisine (1), structurally related to cytisine (2), a benchmark ligand at neuronal nicotinic acetylcholine receptors (NNRs), has been achieved. The synthesis permits the unambiguous confirmation of the structure originally proposed for 1 and has enabled initial biological characterization of 1 and its related compounds against NNRs.
创建时间:
2016-02-27



