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VDR complex of a side-chain hydroxylated derivatives of lithocholic acid

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Protein Data Bank Japan2024-01-31 更新2026-03-28 收录
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VDR complex of a side-chain hydroxylated derivatives of lithocholic acid Descriptor: (3S,6R)-6-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-(2-methyl-2-oxidanyl-propyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]heptane-1,3-diol, Nuclear receptor coactivator 1, Vitamin D3 receptor A Authors: Rochel, N. Deposit date: 2021-06-23 Release date: 2021-09-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR). Bioorg.Chem., 115, 2021
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2021-06-23
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