Conjugate-Base-Stabilized Brønsted Acids: Catalytic Enantioselective Pictet–Spengler Reactions with Unmodified Tryptamine
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下载链接：
https://figshare.com/articles/dataset/Conjugate_Base_Stabilized_Br_nsted_Acids_Catalytic_Enantioselective_Pictet_Spengler_Reactions_with_Unmodified_Tryptamine/2325499
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资源简介：
A conjugate-base-stabilized Brønsted acid facilitates catalytic
enantioselective Pictet–Spengler reactions with unmodified
tryptamine. The chiral carboxylic acid catalyst is readily assembled
in just two steps and enables the formation of β-carbolines
with up to 92% ee. Achiral acid additives or in situ Boc-protection
facilitate catalyst turnover.
创建时间：
2016-02-18
