Crystal Structure of Mnk2-D228G in complex with Inhibitor
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Crystal Structure of Mnk2-D228G in complex with Inhibitor Descriptor: 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION Authors: Han, Q. Deposit date: 2018-02-27 Release date: 2018-05-09 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.32 Å) Cite: Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
创建时间：
2018-02-27
