The role of histone H3K27 acetylation for enhancer activity in embryonic stem cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141525
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资源简介：
By substituting lysine 27 in histone variant H3.3 to arginine in mouse embryonic stem cells, we measured H3K27ac/H3K4me1/H3K4me3 and other acetylation modifications in H3.3K27R mutant cells, together with RNA-seq and ATAC-seq to measure the transcription activity and chromatin accessibility, respectively. WT mouse ESC served as controls , and two H3.3K27R mutant lines (Mut18 and Mut43) were sequenced. Two independent biological replicates were measured for ChIP-seq / RNA-seq /ATAC-seq experiments, and input data were shared among histone ChIP experiments for each cell line.
创建时间：
2020-03-09
