Identification and classification of ion-channels across the tree of life: Insights into understudied CALHM channels
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Description of the data and file structure This dataset includes the curated human ion channel sequences, both the full length and the pore domain sequences, along with a file with fasta sequences for all their identified orthologs. Please refer to the study : https://doi.org/10.7554/eLife.106134.1 for further details. Files and variables File: human_ion_channels.domains.fasta Description: The pore domain sequences for the 343 pore-domain containing human ion channel sequences. File: human_ion_channels.full_length.fasta Description: The full-length sequences for the 419 human ion channel sequences. File: human_ion_channels_orthologs.full_length.fasta Description: Sequences for all the identified orthologs for the pore-containing human ion channel sequences. Code/software A custom annotation pipeline was used to mine, annotate, and curate the presented list of human ion channels. Orthologs were detected using the KinOrtho pipeline.
