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Crystal Structure of the Grb2 SH2 Domain in Complex with a Flexible Ac-pY-Q-N-NH2 Tripeptide Mimic

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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Crystal Structure of the Grb2 SH2 Domain in Complex with a Flexible Ac-pY-Q-N-NH2 Tripeptide Mimic Descriptor: CHLORIDE ION, Growth factor receptor-bound protein 2, MAGNESIUM ION, ... Authors: Clements, J.H. Deposit date: 2009-08-10 Release date: 2009-11-17 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization. J.Am.Chem.Soc., 131, 2009

与柔性Ac-pY-Q-N-NH2三肽模拟物结合的Grb2 SH2结构域晶体结构 描述项:氯离子、生长因子受体结合蛋白2(Growth factor receptor-bound protein 2)、镁离子…… 作者:Clements, J.H. 提交日期:2009-08-10 发布日期:2009-11-17 最后修改日期:2023-09-06 检测方法:X射线衍射(X-RAY DIFFRACTION),分辨率2 Å 引用文献:蛋白质-配体相互作用中构象约束的热力学与结构效应:配体预组织相关的熵悖论,发表于《美国化学会志》(J.Am.Chem.Soc.),第131卷,2009年
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2009-08-10
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