Crystal structure of glycosyltransferase SgUGT94-289-3 in complex with M5, state 2

Crystal structure of glycosyltransferase SgUGT94-289-3 in complex with M5, state 2 Descriptor: (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, (2S,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6R)-6-[[(3S,8S,9R,10R,11R,13R,14S,17R)-17-[(2S,5R)-5-[(2S,3R,4S,5S,6R)-3-[(2R,3R,4S,5S,6S)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6S)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-methyl-6-oxidanyl-heptan-2-yl]-4,4,9,13,14-pentamethyl-11-oxidanyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-3,4,5-tris(oxidanyl)oxan-2-yl]methoxy]oxane-3,4,5-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... Authors: Li, M, Zhang, S, Cui, S. Deposit date: 2022-11-23 Release date: 2024-05-29 Last modified: 2024-08-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural insights into the catalytic selectivity of glycosyltransferase SgUGT94-289-3 towards mogrosides. Nat Commun, 15, 2024

与M5复合物状态2的糖基转移酶（glycosyltransferase）SgUGT94-289-3晶体结构。描述符：(20S)-2,5,8,11,14,17-六甲基-3,6,9,12,15,18-六氧杂二十一烷-1,20-二醇；(2S,3S,4S,5R,6R)-2-(羟甲基)-6-[[(2R,3S,4S,5R,6R)-6-[[(3S,8S,9R,10R,11R,13R,14S,17R)-17-[(2S,5R)-5-[(2S,3R,4S,5S,6R)-3-[(2R,3R,4S,5S,6S)-6-(羟甲基)-3,4,5-三羟基氧杂环己-2-基]氧基-6-[[(2R,3R,4S,5S,6S)-6-(羟甲基)-3,4,5-三羟基氧杂环己-2-基]氧基甲基]-4,5-二羟基氧杂环己-2-基]氧基-6-甲基-6-羟基庚烷-2-基]-4,4,9,13,14-五甲基-11-羟基-2,3,7,8,10,11,12,15,16,17-十氢-1H-环戊并[a]菲-3-基]氧基]-3,4,5-三羟基氧杂环己-2-基]甲氧基]氧杂环己烷-3,4,5-三醇；2-氨基-2-羟甲基丙烷-1,3-二醇，……。作者：Li M、Zhang S、Cui S。沉积日期：2022-11-23。发布日期：2024-05-29。最后修改日期：2024-08-14。测试方法：X射线衍射（X-RAY DIFFRACTION），分辨率2 Å。引用文献：《糖基转移酶SgUGT94-289-3对罗汉果苷催化选择性的结构洞察》，《自然·通讯》，2024年，第15卷。