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BRD9 inhibition overcomes oncolytic virus therapy resistance in glioblastoma

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP484638
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资源简介:
We identified the ncBAF complex as a crucial element in oncolytic virus resistance. Genetic or pharmacological targeting of the ncBAF-specific subunit BRD9 significantly enhanced the potency of oncolytic Herpes Simplex Virus-1 (oHSV1) against glioblastoma.
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2025-08-08
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