Gene expression analysis after GPR17 silencing in oligodendrocyte precursor cells (OPCs). Gene expression analysis after GPR17 silencing in oligodendrocyte precursor cells (OPCs)

GPR17 silencing in OPCs accelerates their differentiation into fully mature oligodendrocytes. We performed a whole microarray profiling to identify altered signaling pathways after GPR17 silencing that are responsible for its effect on oligodendrocyte maturation. Overall design: Gene expression was measured in OPCs 48h after transfection of GPR17 siRNA (or negative control). 2 independent samples were used for each condition.