Crystal Structure of Human IDO1 bound to navoximod (NLG-919)
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal Structure of Human IDO1 bound to navoximod (NLG-919) Descriptor: Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, trans-4-{(1R)-2-[(5S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexan-1-ol Authors: Harris, S.F, Oh, A. Deposit date: 2019-02-26 Release date: 2019-07-17 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Discovery of Clinical Candidate (1R,4r)-4-((R)-2-((S)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol (Navoximod), a Potent and Selective Inhibitor of Indoleamine 2,3-Dioxygenase 1. J.Med.Chem., 62, 2019
创建时间：
2019-02-26
