Additional file 23 of Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS

Additional file 23. Results from analyses of previously published candidate SNPs and HLA alleles. Variants, alleles, and the respective p-values are labeled in bold font if they showed a one-sided p < 2.5 × 10− 3 (Bonferroni correction for 20 tests) either in the pooled analysis across treatment preparations or in the analysis of IFNβ-1a s.c.-treated or IFNβ-1b s.c.- treated patients. “nADA titer in nADA-positive” refers to an analysis of nADA titers restricted to nADA-positive patients. All effect sizes are relative to the minor allele. Bp = base pairs, MAF = minor allele frequency, AF = allele frequency, beta = regression effect size, SE = standard error, P = p-value, cond. = conditional analysis.