Enucleated oocytes have the remarkable ability to reprogram somatic nuclei back to totipotency. Here we investigate genome-scale DNA methylation patterns after nuclear transfer and identify specific t

NIAID Data Ecosystem30

Additional file 3: of Transcriptional defects and reprogramming barriers in somatic cell nuclear reprogramming as revealed by single-embryo RNA sequencing

基因表达分析

细胞核重编程

List of different genes between NT groups and Invivo group. Two group Ensembl gene IDs were listed. One is different genes between NTC embryos and Invivo embryos. The other is different genes between

DataCite Commons2024-02-20 更新80

Chemical reprogramming of human blood cells into hCiPS cells [bulk ATAC-seq]

细胞重编程

干细胞生成

Chemical reprogramming offers a fundamentally innovative approach for generating human pluripotent stem (hCiPS) cells using small molecules. Our recent studies showed that this approach was highly eff

NIAID Data Ecosystem30

Human oocytes reprogram adult somatic nuclei to diploid pluripotent stem cells

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