Characterization of a microbial mock community through hybridization capture

We developped a new hybridization capture strategy that uses a set of probes targeting all known 16S rRNA gene bacterial and archaeal diversity to enrich the full-length biomarker and to explore the microbial diversity of metagenomic samples . To evaluate the efficiency of this strategy, we applied this approach to a microbial mock community and we compared it to 16S rRNA gene amplicon sequencing and shotgun sequencing approaches.