Streptococcus mutans transcriptome in the presence of sodium fluoride and sucrose

Considering the diverse mechanisms by which fluoride could affect oral bacteria, this study evaluated the effect of sodium fluoride on Streptococcus mutans UA159 transcriptome in the presence of sucrose, using a high-throughput mRNA-sequencing.S. mutans UA159 was cultured in 3 different types of media: medium control group [Tryptone-yeast], sucrose control group [Tryptone-yeast + 10mM sucrose], and sodium fluoride sucrose test group [Tryptone-yeast + 10mM sucrose + 100ppm NaF].