Structure of CHK1 10-pt. mutant complex with LRRK2 inhibitor 06
收藏Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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Structure of CHK1 10-pt. mutant complex with LRRK2 inhibitor 06 Descriptor: 1,2-ETHANEDIOL, 8-cyclopropyl-N-[5-methyl-1-(oxan-4-yl)-1H-pyrazol-4-yl]quinazolin-2-amine, Serine/threonine-protein kinase Chk1 Authors: Palte, R.L. Deposit date: 2021-11-17 Release date: 2022-01-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. J.Med.Chem., 65, 2022
创建时间：
2021-11-17
