Local refinement of the N-terminal domain (NTD) and receptor binding domain (RBD) from the Porcine hemagglutinating encephalomyelitis virus (PHEV) Spike in the closed conformation bound to 9-O-Ac-Sia
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Local refinement of the N-terminal domain (NTD) and receptor binding domain (RBD) from the Porcine hemagglutinating encephalomyelitis virus (PHEV) Spike in the closed conformation bound to 9-O-Ac-Sia Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, Spike glycoprotein, ... Authors: Fernandez, I, Rey, F.A. Deposit date: 2025-05-13 Release date: 2025-08-06 Last modified: 2025-11-12 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Dipeptidase 1 is a functional receptor for a porcine coronavirus. Nat Microbiol, 10, 2025
猪血凝性脑脊髓炎病毒(Porcine hemagglutinating encephalomyelitis virus, PHEV)闭合构象刺突蛋白(Spike)与9-O-乙酰化唾液酸(9-O-Ac-Sia)结合复合物的N端结构域(N-terminal domain, NTD)及受体结合域(receptor binding domain, RBD)局部精修。配体描述项:2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、9-O-乙酰基-5-乙酰氨基-3,5-二脱氧-D-甘油-α-D-半乳糖-壬-2-吡喃糖醛酸、刺突糖蛋白等。作者:Fernandez, I、Rey, F.A.。存入日期:2025年5月13日;发布日期:2025年8月6日;最后修改日期:2025年11月12日。研究方法:电子显微镜(分辨率3.5 Å)。引用文献:二肽基肽酶1是一种猪冠状病毒的功能性受体。《自然·微生物学》(*Nat Microbiol*),第10卷,2025年。



