Analysis of changes in the expression of genes involved in wnt-signaling.
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Total RNA isolated from tumors of WAP-T transgenic and WAP-mutCK1δ/WAP-T bi-transgenic animals was transcribed into complementary DNA. Gene profiling was done using RT2 profiler PCR array “mouse wnt-signaling pathway” (84 genes) (Superarray SABioscience, Karlsruhe, Germany). The values represent the mean of the observed changes in gene expression in tumors of WAP-T and WAP-mutCK1δ/WAP-T mice compared to the according non-tumor control tissue. Data are presented as ± standard error of the mean (SEM). Increased expression: ↑; decreased expression: ↓.
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2015-12-02



