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A randomized phase II study of pulsatile high-dose sunitinib versus TAS-102 in patients with metastatic colorectal carcinoma (mCRC).

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下载链接:
https://www.omicsdi.org/dataset/ecrin-mdr-crc/2442614
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资源简介:
Interventions: A: TAS-102 (Lonsurf) 35 mg per square meter, twice daily, 5 days a week, with 2 days of rest, for 2 weeks, followed by a 14-day rest period. B: Experimental: High Dose Intermittent Sunitinib 700 mg once every 2 weeks. Primary outcome(s): The primary objective of this study is to improve progression free survival (PFS), of patients with metastatic colorectal carcinoma (mCRC) treated with high-dose sunitinib once every 2 weeks to 5 months, compared to the reported 2 months for TAS-102 monotherapy. Study Design: Randomized controlled trial, Open (masking not used), Active, Parallel
创建时间:
2019-10-15
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