Analysis of selected DUB expression in melanoma progression.

Correlation between DUB expression and clinico-pathological parameters in melanomas. Expression was measured by ISH-TMA (Negative (NEG), ISH score≤1; Positive (POS), ISH score>1). P-values were measured as in Table 1. Note that the number of scored cases is lower than the total number of cases (see Table 1). Histotypes: NM, nodular melanoma; SSM, superficial spreading melanoma. TIL: tumor-infiltrating lymphocytes. In all melanomas (including metastatic ones), the ISH signals were associated with the tumor cell component and not with the adjacent or infiltrating stroma.