Proteomic analysis of HDL isolates reveals method-driven variability between ultracentrifugation and immunoaffinity chromatography: an interlaboratory approach

Therefore, the aim of our study is to systematically compare the effect of two different methods of HDL isolation, namely UC and IAC, performed in two independent research laboratories. For this purpose, we used the same plasma pool and protocols optimized to evaluate the influence of those variables in HDL proteome composition.