Cγ and lupanine enhances in vivo the antidiabetic effect and involves modulation of the liver gene expression profile

Alliance of Genome Resources2026-08-01 收录

糖尿病机制

肝脏基因表达分析

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https://www.ncbi.nlm.nih.gov/gds/?term=GSE216668 数据链接链接失效反馈

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Gene expression analysis of RNA samples from liver tissue of healthy and diabetic-induced rats.

Table_1_Exploring novel targets of sitagliptin for type 2 diabetes mellitus: Network pharmacology, molecular docking, molecular dynamics simulation, and SPR approaches.docx

药物靶点发现

糖尿病机制

BackgroundDiabetes has become a serious global public health problem. With the increasing prevalence of type 2 diabetes mellitus (T2DM), the incidence of complications of T2DM is also on the rise. Sit

NIAID Data Ecosystem20

糖尿病机制

肾小球内皮功能障碍

The files contain all the dataset included in the manuscript divided by figures. Abstract In addition to having blood glucose-lowering effects, inhibitors of sodium glucose cotransporter 2 (SGLT2)

Zenodo2022-02-23 更新10

Insulin post-transcriptional regulation via PARP12-mediated ADP-ribosylation

转录后调控

糖尿病机制

ADP-ribosylation is a common modification that occurs in proteins and nucleic acids, regulating many cellular processes ranging from DNA repair to inflammatory signaling. ADP-ribosylation plays an imp

NIAID Data Ecosystem00

DataSheet_2_Bioinformatics Analysis of the Mechanisms of Diabetic Nephropathy via Novel Biomarkers and Competing Endogenous RNA Network.pdf

糖尿病机制

ceRNA网络

Diabetic nephropathy (DN) is one of the common chronic complications of diabetes with unclear molecular mechanisms, which is associated with end-stage renal disease (ESRD) and chronic kidney disease (

NIAID Data Ecosystem20

Effect of high fat diet on gene expression in pancreatic islet associated macrophages

巨噬细胞

糖尿病机制

We have exploited islet-associated macrophages (IAMs) as a model of resident macrophage function, focusing on more physiological conditions than the commonly used extremes of M1 (inflammation) versus

NIAID Data Ecosystem10

Cγ and lupanine enhances in vivo the antidiabetic effect and involves modulation of the liver gene expression profile

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