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mouse sciatic nerve profile of CMT1A peripheral neuropathy model, caused by PMP22 overexpression

NIAID Data Ecosystem2026-03-07 收录

周围神经病变模型

PMP22过表达

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1962 数据链接链接失效反馈

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资源简介：

profiles of normal and diseased sciatic nerve of young adult mice Keywords: other

应用场景：

创建时间：

2012-03-15

周围神经病变模型

施万细胞疾病机制

Three CMT1A patient Schwann cell populations which were derived from hESC, hiPSC, or direct converted hiNC share the disease relevant phenotypes. From comparing deep sequencing results of these popula

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Expression data for 2-month-old wild type and Tfam-SCKO (MPZ-Tfam KO) sciatic nerves. Mus musculus

周围神经病变模型

施万细胞线粒体功能

Gene expression analysis of 2-month-old Ctrl and Tfam-SCKO mice. At this age mitochondrial function is disrupted in the Schwann cells of Tfam-SCKO mice ,but their nerves display only very limited path

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RNA-Seq of rat dorsal root ganglions treated with paclitaxel against untreated controls

周围神经病变模型

转录组分析

L4-L5 segment dorsal root ganglion (DRG) samples from controls and the paclitaxel-induced peripheral neuropathy (PIPN) rats were collected at day 14 after the initiation of paclitaxel treatment. Pacli

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PAK1 inhibitor PF-3758309 is therapeutic in the Pmp22+/- mice

周围神经病变模型

药物疗效评估

PAK1 inhibitor PF-3758309 is therapeutic in the Pmp22+/- mice

NIAID Data Ecosystem50

Disease mechanisms in peripheral neuropathies due to altered Pmp22 gene dosage or a Pmp22 point mutation. Mus musculus

周围神经病变模型

基因表达谱分析

We compared gene expression at ages P4 and P60 in sciatic nerve of wild type mice and mice with peripheral neuropathies caused by altered Pmp22 gene dosage (homozygous knockout or transgene) or a poin

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mouse sciatic nerve profile of CMT1A peripheral neuropathy model, caused by PMP22 overexpression

资源简介：

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