Meerkat MHC-TB coevolution, Datasets and Code

Data and code used for the analyses of the manuscript titled "Twenty-year co-evolutionary arms race between meerkat MHC and Tuberculosis".

Included files: Sus-DRB.fasta.txt -> Fasta file of nucleotide sequences of MHC-DRB alleles of 1567 successfully MHC-genotpyed meerkats.
Allele_NT_sequences: Overview of MHC-DRB alleles of 1567 successfully MHC genotyped meerkats, including all identifiers used for the respective sequence throughout analyses and Figures. Nucloeotide_sequence = raw nucleotide sequence, nucleotide_sequence_modified: Nucleotide sequence without the first Base, as Open Reading Frame of the sequence began on position 2, so first base was excluded prior to further analyses.
Metafiles_meerkats_MHC_TB.xls: Detailed information on the variables included in the datasets provided.
MHC_TB_R_Script.Rmd: R-Markdown file including the code used for data filtering and analyses for all models run for the manuscript.
MHC_summary_year_NFDS: Data used to test for negative frequency dependent selection on MHC allele DRB*13 and the corresponding supertype ST09 and haplotype F. Data on yearly frequency on the respective MHC measure and TB prevalence as well as TB prevalence in the following year and the difference between TB prevalences between following years.
MHC_TB_analyses.RData: Workspace including the datasets used for analyses for the manuscript.