RNA profiles of MOLM-13 cells treated with FLT3 inhibitor in the presence of conditioned media of bone marrow stromal cells

RNA-seq analysis of MOLM-13 cells to compare the gene expression profiles post FLT3 inhibition and/or ATM inhibition in the presence or absence of conditioned media of bone marrow stromal cell HS-5 Overall design: MOLM-13 cells were treated with 3nM FLT3 inhibitor quizartinib and/or 3uM ATM inhibitor AZD1056 for 15 hours in the presence of either RPMI (regular media) or hBMSC-CM (conditioned media of human bone marrow stromal cell line HS-5). Using RNAs isolated from each treatment condition, we performed transcriptome analysis.