The effect of high fat diet on mouse prostate development
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE260450
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Steroid 5α reductase 2 (SRD5A2) is the predominant enzyme responsible for prostatic development and growth. Despite the introduction of steroid 5α-reductase inhibitors (5ARI) for benign prostatic hyperplasia (BPH), the progression of LUTS is only slowed by 34% with 5ARI-response. Previous literature establishes link between obesity and BPH progression. We hypothesize that high fat diet is associated with prostate development. Single-cell RNA sequencing of fresh mouse prostate samples
创建时间：
2024-03-04
