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The C-terminal region of Xpc is dispensable for the transcriptional activity of Oct3/4 in mouse embryonic stem cells

ChEBI2015-06-09 更新2026-07-12 收录

干细胞转录调控

胚胎干细胞功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-69640 数据链接链接失效反馈

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The C-terminal region of Xpc is dispensable for the transcriptional activity of Oct3/4 in mouse embryonic stem cells

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创建时间：

2015-06-09

转录调控机制

胚胎干细胞功能

RNA-seq of hnRNP K-depleted mouse embryonic stem cells RNA-seq was performed on two biological replicates of control- or Hnrnpk siRNA-transfected TT2 ES cells, 72 h post transfection.

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Development of a method for quantitative analysis of in vivo interactions of pluripotency transcription factors Sox2, Oct4, Nanog by mass spectrometry

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Protein-protein proximity of core pluripotency transcription factors plays an important role during cell reprogramming. Pluripotent embryonic stem (ES) cell identity is controlled by a trio of transcr

NIAID Data Ecosystem50

Transcriptome analysis of histone demethylase Kdm2a knockout in mouse embryonic stem cells

表观遗传调控

胚胎干细胞功能

H3K36 methylation plays an important role in gene regulation. The role of H3K36 demethylase Kdm2b has been well studied. However, the role of Kdm2a in embryonic stem cells are still unkonwn. To study

NIAID Data Ecosystem40

CRISPR Reveals a Distal Super-Enhancer Required for Sox2 Expression in Mouse Embryonic Stem Cells

干细胞转录调控

CRISPRi功能基因组学

The pluripotency of embryonic stem cells (ESCs) is maintained by a small group of master transcription factors including Oct4, Sox2 and Nanog. These core factors form a regulatory circuit controlling

NIAID Data Ecosystem70

MYSM1 maintains ribosomal protein gene expression in hematopoietic stem cells to prevent hematopoietic dysfunction I.

干细胞转录调控

核糖体蛋白基因

MYSM1 is a transcriptional regulator essential for HSC function and hematopoiesis. We established that HSC dysfunction in Mysm1-deficiency is driven by p53 stress response, however, the molecular func

NIAID Data Ecosystem40

The C-terminal region of Xpc is dispensable for the transcriptional activity of Oct3/4 in mouse embryonic stem cells

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