Single Cell sequencing analysis of AT1/AT2 cells from wildtype mouse, AT1-Cdc42 knockout mouse, and left bronchial ligation model

The goal of this study was to compare wildtype adult lung epithelium to epithelium from Cdc42 AT1-KO mice and mice after left bronchial ligation model. Overall design: Two samples of adult mouse epithelial cells, three samples of adult Hopx-CreERT2; Cdc42 KO lineage traced mice, and three samples of Hopx-CreERT2 lineage traced mice after left bronchial ligation were pooled respectively for library preparation.