five

Changes in DNA methylation In cultered WI-38 cells over passages

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NIAID Data Ecosystem2026-03-06 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE30640
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We used Illumina infinium methylation array analysis to document spontaneous DNA methylation changes in human fibroblasts growing in long term culture. Starting with a culture derived from a single cell we compared the methylation profile of late passage clones with that of the initial culture, allowing unambiguous identification of methylation changes. Bisulphite converted DNA from the 5 samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip v1.2
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2015-01-02
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