Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... Authors: Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. Deposit date: 2018-11-05 Release date: 2018-11-14 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018

生殖系VRC01抗体识别修饰后C亚型人类免疫缺陷病毒1型（HIV-1）包膜三聚体，结合2个Fab片段（Fragment antigen binding, Fab），经锐化处理的电镜密度图。
描述符（Descriptor）：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、426c DS-SOSIP D3……
作者：Borst, A.J.、Weidle, C.E.、Gray, M.D.、Frenz, B.、Snijder, J.、Joyce, M.G.、Georgiev, I.S.、Stewart-Jones, G.B.E.、Kwong, P.D.、McGuire, A.T.、DiMaio, F.、Stamatatos, L.、Pancera, M.、Veesler, D.
存放日期：2018-11-05；发布日期：2018-11-14；最后修改日期：2024-11-13
实验方法：电子显微镜（4.8 Å）
引用文献：《生殖系VRC01抗体识别修饰后C亚型HIV-1包膜三聚体与糖基化HIV-1 gp120核心蛋白》，《eLife》，第7卷，2018年