RNA-seq normalized count matrix from TgA86 spondyloarthritis mouse model
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DESeq2-normalized count matrix from RNA sequencing of spine bones from TgA86 transgenic mice (transmembrane TNF-alpha overexpression model of spondyloarthritis) and wild-type controls at 4 and 10 months of age (5 biological replicates per group, 20 samples total). Sequenced on Illumina NovaSeq 6000 (paired-end, 2x150 bp). Reads were aligned to GRCm39 (Mus musculus) using STAR aligner (v2.7.3a), quantified with HTSeq-Count (v0.12.4), and normalized with DESeq2 (v1.44.0). This dataset is associated with the manuscript: "TgA86 mouse model demonstrated potential markers for bone formation in Spondyloarthritis through ROS Detoxification, Folate Metabolism, and Inositol Phosphate Metabolism.
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Zenodo创建时间：
2026-03-12
