Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC063)

Trypanosoma cruzi Malic Enzyme in complex with inhibitor (MEC063) Descriptor: 3,5-bis(fluoranyl)-~{N}-[3-[[4-(trifluoromethyloxy)phenyl]sulfamoyl]phenyl]benzamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Malic enzyme Authors: Mercaldi, G.F, Fagundes, M, Faria, J.N, Cordeiro, A.T. Deposit date: 2020-03-12 Release date: 2021-03-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box. Acs Infect Dis., 7, 2021

本数据集的研究对象为与抑制剂（MEC063）结合的克氏锥虫（Trypanosoma cruzi）苹果酸酶（Malic Enzyme）；数据集描述的化学物质包括：3,5-二氟-N-[3-[[4-(三氟甲氧基)苯基]磺酰胺基]苯基]苯甲酰胺、4-(2-羟乙基)-1-哌嗪乙磺酸、苹果酸酶；作者为Mercaldi, G.F、Fagundes, M、Faria, J.N、Cordeiro, A.T.；存入日期：2020-03-12；发布日期：2021-03-17；最后修改日期：2023-10-18；解析方法为X射线衍射（X-RAY DIFFRACTION），分辨率1.95埃；引用文献：《Trypanosoma cruzi Malic Enzyme Is the Target for Sulfonamide Hits from the GSK Chagas Box》，发表于Acs Infect Dis., 7, 2021。