Robust correspondence of automated membrane segmentations with automated nuclear segmentations.

Detection and error rates of the automated algorithm was compared with standard nuclear segmentation algorithms. The assumption was that perfect segmentations of both algorithms should theoretically establish a one-to-one correspondence between nuclei and membranes detected. Matched refers to cells with membrane and nuclei in exact correspondence. Unmatched Cells refer to membranes that did not contain a unique nucleus. Unmatched Nuclei refer to nuclei that did not correspond to a cell membrane.