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Crystal structure of Bcl-xL in complex with the BIM BH3 domain containing Ile155-to-Arg and Glu158-to-phosphoserine mutations

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Protein Data Bank Japan2025-04-09 更新2026-03-21 收录
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Crystal structure of Bcl-xL in complex with the BIM BH3 domain containing Ile155-to-Arg and Glu158-to-phosphoserine mutations Descriptor: ACETATE ION, Bcl-2-like protein 1, BIM BH3 domain, ... Authors: Ku, B, Ha, N.-C, Oh, B.-H. Deposit date: 2015-03-03 Release date: 2015-07-29 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Conversion of cell-survival activity of Akt into apoptotic death of cancer cells by two mutations on the BIM BH3 domain. Cell Death Dis, 6, 2015

携带Ile155→精氨酸及Glu158→磷酸丝氨酸突变的BIM BH3结构域与Bcl-xL结合的晶体结构 描述符:乙酸根离子(ACETATE ION)、Bcl-2样蛋白1(Bcl-2-like protein 1)、BIM BH3结构域…… 作者:Ku, B、Ha, N.-C、Oh, B.-H. 保藏日期:2015-03-03 发布日期:2015-07-29 最后修改日期:2025-04-09 实验方法:X射线衍射(X-RAY DIFFRACTION,2.1 Å) 引用文献:《通过BIM BH3结构域上的两处突变将Akt的细胞存活活性转化为癌细胞凋亡死亡》,《细胞死亡与疾病(Cell Death Dis)》,2015年,第6卷
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2015-03-03
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