One-Pot Synthesis of Hypervalent Iodine Reagents for Electrophilic Trifluoromethylation
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https://figshare.com/articles/dataset/One_Pot_Synthesis_of_Hypervalent_Iodine_Reagents_for_Electrophilic_Trifluoromethylation/2398417
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资源简介：
Simplified syntheses suited for large
scale preparations of the
two hypervalent iodine reagents 1 and 2 for
electrophilic trifluoromethylation are reported. In both cases, the
stoichiometric oxidants sodium metaperiodate and tert-butyl hypochlorite have been replaced by trichloroisocyanuric acid.
Reagent 1 is accessible in a one-pot procedure from 2-iodobenzoic
acid in 72% yield. Reagent 2 was prepared via fluoroiodane 11 in a considerably shorter reaction time and with no need
of an accurate temperature control.
创建时间：
2016-02-19
