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Revealing modifications of asbestos after prolonged stay in the lungs

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ESRF Portal2027-01-01 更新2026-04-23 收录
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https://doi.esrf.fr/10.15151/ESRF-ES-1749478546
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资源简介:
The knowledge of the toxic and carcinogenic mechanisms of asbestos in living organisms is still incomplete, also due to the poor understanding of the asbestos modifications during its prolonged stay in the biological tissue. To gain new knowledge on the structural modifications of asbestos, and on the chemical composition of the Fe-coating it develops in the tissues (asbestos body), we propose to perform nano-X-ray powder diffraction (nano-XRPD) measurements on asbestos fibers (AF) and asbestos bodies (AB) embedded in lung tissue samples from human subjects who were occupationally exposed to asbestos for years. The proposed experiment is a continuation of experiment LS3009, whose results have been recently published. The aim of this new experiment is to extend the number of samples to generalize the previously obtained results.
提供机构:
CNR-Institute of Nanotechnology,c/o Physics Department 'Sapienza' University,Via Cineto Romano 42,Piazzale Aldo Moro 5,00185 ROMA,00185,ROMA,ITALY; Universita di Roma La Sapienza,Dipartimento di Scienze della Terra,Piazzale Aldo Moro 5,00185 ROMA,ITALY,00185 ,ROMA,ITALY; I.R.C.C.S. Burlo Garofolo Children s Hospital,Department of Molecular Medicine,Via dell Istria 65/1,34137 TRIESTE,ITALY,34137,TRIESTE,ITALY
创建时间:
2027-01-01
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