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Mice Pcsk9 indels treated by PEG10 VLPs

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1063607
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资源简介:
NGS sequencing reads for C57BL/6JTshu mice liver tissues treated by in-vein injection of virus-like particles (VLPs) containing spCas9 mRNA and gRNA(Pcsk9) to generate in vivo knockouts. The VLPs were generated using naive PEG10 (SEND) or our optimized PEG10 variant (FedEx-MCP). PBS psudotreatment groups were included. The data highlights that our optimized PEG10 generates significantly higher indel rates than the naive PEG10.
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2024-01-11
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