MOESM1 of An epigenome-wide association study of sex-specific chronological ageing
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Additional file 1: Tables S1-S10: Top 1000 autosomal probe associations for chronological age present in both discovery and replication cohorts, using the linear regression model, ranked by discovery P-value. Table headers correspond to Limma TopTable outputs - Table S1. Top 1000 X-linked probe associations for chronological age present in the discovery and replication cohorts, using the linear regression model, ranked by discovery P-value. Table headers correspond to Limma TopTable outputs - Table S2. Top 1000 autosomal probe associations for sex present in both discovery and replication cohorts, using the linear regression model, ranked by discovery P-value. Table headers correspond to Limma TopTable outputs - Table S3. Top 1000 autosomal probe associations for the age-by-sex interaction present in both discovery and replication cohorts, using the linear regression method, ranked by discovery P-value. Table headers correspond to Limma TopTable outputs - Table S4. Top 1000 X-linked probe associations for the age-by-sex interaction present in both discovery and replication cohorts, using the linear regression approach, ranked by discovery P-value. Table headers correspond to Limma TopTable outputs - Table S5. Epigenome-wide significant sites associated with the age-by-sex interaction with concordant effects in the discovery and replication cohorts identified using the conservative mixed-modelling approach - Table S6. GWAS catalogue outputs within 1 Mb of age-by-sex-associated CpGs - Table S7. ARIES mQTLdb output for query containing age-by-sex-associated CpGs - Table S8. KEGG pathway enrichment output for age-by-sex-associated sites - Table S9. GO Term enrichment output for age-by-sex-associated sites - Table S10.
提供机构:
Walker, Rosie; Hillary, Robert; Marioni, Riccardo; Yang, Jian; Hayward, Caroline; Zhang, Qian; Stevenson, Anna; Campbell, Archie; Morris, Stewart; Murray, Alison; Whalley, Heather; Boutin, Thibaud; Evans, Kathryn; Chandra, Tamir; Visscher, Peter; Bermingham, Mairead; Zhang, Futao; Porteous, David; Deary, Ian; McIntosh, Andrew; McRae, Allan; McCartney, Daniel
创建时间:
2020-01-01



