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Diastereoselective Synthesis of Functionalized Tetrahydrocarbazoles via a Domino-Ring Opening–Cyclization of Donor–Acceptor Cyclopropanes with Substituted 2‑Vinylindoles

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Figshare2016-02-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Diastereoselective_Synthesis_of_Functionalized_Tetrahydrocarbazoles_via_a_Domino_Ring_Opening_Cyclization_of_Donor_Acceptor_Cyclopropanes_with_Substituted_2_Vinylindoles/2269324
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资源简介:
A new domino synthetic approach for the synthesis of highly functionalized tetrahydrocarbazoles via DROC of various functionalized DA-cyclopropanes with 2-indolylnitroethylene and indole-substituted alkylidene malonate is described. The tetrahydrocarbazoles were obtained with excellent diastereoselectivity having cis alignment of the 1,4-appendages across the six-membered carbocyclic ring.
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2016-02-17
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