X-ray structure of human acetylcholinesterase ternary complex with paraoxon and oxime RS170B (POX-hAChE-RS170B)

X-ray structure of human acetylcholinesterase ternary complex with paraoxon and oxime RS170B (POX-hAChE-RS170B) Descriptor: 4-carbamoyl-1-(3-{2-[(E)-(hydroxyimino)methyl]-1H-imidazol-1-yl}propyl)pyridin-1-ium, Acetylcholinesterase, DIETHYL PHOSPHONATE, ... Authors: Kovalevsky, A.Y, Gerlits, O, Radic, Z. Deposit date: 2022-07-25 Release date: 2022-11-02 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering. Structure, 30, 2022

人类乙酰胆碱酯酶（Acetylcholinesterase）与对氧磷及肟RS170B形成的三元复合物的X射线晶体结构（POX-hAChE-RS170B）。描述符：4-氨基甲酰基-1-(3-{2-[(E)-(羟亚氨基)甲基]-1H-咪唑-1-基}丙基)吡啶鎓、乙酰胆碱酯酶、二乙基磷酸酯……。作者：科瓦列夫斯基（Kovalevsky, A.Y）、格尔利茨（Gerlits, O）、拉迪克（Radic, Z）。提交日期：2022-07-25，发布日期：2022-11-02，最后修改日期：2024-11-13。实验方法：X射线衍射（分辨率2.6 Å）。引用：《通过X射线晶体学与非弹性中子散射研究对氧磷结合人类乙酰胆碱酯酶的结构与动态效应》，《Structure》，第30卷，2022年。