ChIP-seq data in MSC_Pat and EWIma1 (FLI1 & H3K27ac)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE150776
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资源简介：
Ewing sarcoma is characterized by pathognomonic translocations fusing most frequently EWSR1 with FLI1 (EF1). In addition, Ewing sarcoma can also display alterations in STAG2, TP53 and CDKN2A (SPC). Starting from Ewing sarcoma derived human mesenchymal stem cells (MSCpat), we recapitulated this translocation and SPC alterations using a CRISPR/cas9 approach and generated a bona fide Ewing sarcoma model (EWIma1) displaying transcriptomic and epigenetic hallmarks of EwS. ChIP-seq (FLI1 and H3K27ac) were performed in MSC_Pat and EWIma1 cells. Respective inputs were used as normalization controls.
创建时间：
2021-11-17
