Single Patient BRAF Mutant Brain Tumor, Pre- and Post-dabrafenib WES.

A single adolescent patient with a BRAF V600E mutated brain tumor was treated with dabrafenib and had a complete response, followed by progression. The pre-treatment and post-progression tumors were both sequenced in order to identify potential drivers of resistance.]]> The patient had both pre-treatment and post-progression specimens available for research use.]]> A single adolescent patient with a BRAF V600E mutated brain tumor was treated with dabrafenib and had a complete response, followed by progression. The pre-treatment and post-progression tumors were both sequenced in order to identify potential drivers of resistance.]]>