Multivariate correlation between evolutionary and clinical factors.
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Macaques 1–12 were assigned ranks based on clinical and evolutionary parameters. Corrected p values are given where p<0.05 indicates statistical significance*.
aMid = 6.5 months p.i.
bLate = 14 months p.i.
cThe potency is the mean of the magnitudes for each macaque against SIV, HIV-2 and HIV-1 shown in Table 2.
dMean sequence divergence from SIVmac239 over all time points, estimated under CTR+γ+I.
eMean diversity as determined by mean site-wise Shannon entropy in each subject sequence alignment over all time points.
fDecline in CD4+ T-cell numbers from start of study to 6.5 months p.i.
gTotal CD4+ T-cell count at 6.5 months.
hTotal number of positively-selected sites in each subject's sequences.
iNAb SIVsm:SMM-3 titer 4.5 months p.i.
jIntegral of PGD during treatment period.
kIntegral of PGD over duration of study.
创建时间:
2010-09-02



